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  • Title: [The role of portal hypertension and colloid-osmotic blood pressure in the pathogenesis of ascitis in patients with hepatic cyrrhosis].
    Author: Kotiv BN, Basov SP.
    Journal: Klin Med (Mosk); 2006; 84(3):46-9. PubMed ID: 16758923.
    Abstract:
    The subjects of the study were 27 patients with hepatic cirrhosis and portal hypertension syndrome. Laboratory and instrumental diagnostic methods routinely used in this pathology were applied: calculation of colloid-osmotic pressure; portal pressure measurement, intraoperationally and using phlebohepatomanometry. The data were processed using STATISTIKA program. The results show that: 1. Ascitic syndrome manifestations do not depend on either the pressure in the v. porta nor oncotic pressure (insignificant difference between the groups); 2. Filtration gradient (FG), which is a physiological variable that determine the liquid movement in splanchnic capillaries, was significantly higher in ascitic patients (p < 0.05); FG correlates with the presence of ascitis (r = 0.5, p < 0.05); 3. FG after portacaval shunting facilitates the resolution of ascitis.
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