These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Giant cell interstitial pneumonia: a case report and literature review].
    Author: Cai HR, Cao M, Meng FQ, Wei JY, Hou J.
    Journal: Zhonghua Jie He He Hu Xi Za Zhi; 2006 May; 29(5):313-6. PubMed ID: 16759488.
    Abstract:
    OBJECTIVE: To highlight the characteristics of giant cell interstitial pneumonia (GIP). METHODS: The clinical, radiological and pathological data of a patient with GIP confirmed by open lung biopsy were presented, and relevant literatures were reviewed. RESULTS: Patients with GIP usually had a history of exposure to metal dust. Clinical presentations include cough and dyspnea on exertion, and pulmonary function testing showed a restrictive abnormality. On chest radiography and high-resolution CT scans, it presents as bilateral areas of ground-glass attenuation, areas of consolidation, diffuse small nodules, extensive reticular opacities and traction bronchiectasis. The main pathological findings include a desquamative interstitial pneumonia (DIP)-like reaction with intra-alveolar macrophages and numerous large multinucleated histiocytes that ingested inflammatory cells were admixed with macrophages. The finding of GIP is almost pathognomonic for hard metal pneumoconiosis. CONCLUSIONS: GIP is a very rare chronic interstitial pneumonia, and has no characteristic clinical manifestations. Radiographic findings are similar to other idiopathic interstitial pneumonias. Meticulous history taking on occupational exposure is important for the diagnosis of GIP.
    [Abstract] [Full Text] [Related] [New Search]