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  • Title: Hemoglobin E-thalassaemia in a Sikh child: a case report.
    Author: Kakkar N.
    Journal: Indian J Pathol Microbiol; 2005 Jul; 48(3):408-10. PubMed ID: 16761772.
    Abstract:
    Hemoglobin E is a beta chain variant that has its most clinically significant interaction with thalassaemia. The compound heterozygous state, thus produced, can result in a thalassaemia intermedia/major phenotype with affected individuals being transfusion dependent. Hemoglobin E is very common in north-east India with relatively fewer reportsfrom rest of the country. Reports of hemoglobin E in the Punjabi population are even rarer. A case of hemoglobin E-thalassaemia in a Sikh child is being presented because of its highly uncommon occurrence in natives of Punjab.
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