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  • Title: [Evaluation of fetal lung maturity with the measurement of enzymatic activities in amniotic fluid: comparison of three ratios].
    Author: Forzy G, Houze de l'aulnoit D, Brabant G, Ellart D, Dhondt JL, Delcroix M.
    Journal: Ann Biol Clin (Paris); 1991; 49(2):105-7. PubMed ID: 1676568.
    Abstract:
    Measurement, in amniotic fluid, of gamma-glutamyl-transferase (GGT) alkaline phosphatase and of thermostable and thermolabile (TLAP) isoenzyme allows to anticipate the unexpected risk of hyaline membrane disease. ROC method adapted to three ratio of these enzymatic activities shows that TLAP/GGT is the most performant at the level of 0.9 with a sensitivity of 96% and a specificity of 60%.
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