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  • Title: Combination chemotherapy with cyclophosphamide, thalidomide and dexamethasone for patients with refractory, newly diagnosed or relapsed myeloma.
    Author: Sidra G, Williams CD, Russell NH, Zaman S, Myers B, Byrne JL.
    Journal: Haematologica; 2006 Jun; 91(6):862-3. PubMed ID: 16769594.
    Abstract:
    We evaluated the combination of thalidomide, pulsed dexamethasone and weekly cyclophosphamide (CTD) for the treatment of patients with newly diagnosed, relapsed or VAD-refractory multiple myeloma. We found that this combination was highly effective in inducing responses in all treatment groups with an overall response rate of 83.8%. CTD was well tolerated and did not impair stem cell mobilization.
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