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  • Title: Usefulness of pneumococcal antigen detection in pleural fluid samples by immunochromatographic assay for diagnosis of pneumococcal pneumonia.
    Author: Andreo F, Domínguez J, Ruiz-Manzano J, Prat C, Blanco S, Lores L, Sánchez MD, Latorre I, Giménez M, Ausina V.
    Journal: Clin Microbiol Infect; 2006 Jul; 12(7):682-4. PubMed ID: 16774569.
    Abstract:
    This study investigated the utility of an immunochromatographic test (ICT) for the detection of Streptococcus pneumoniae antigens in pleural fluid. Antigen was detected in 15 of 19 (79%) patients with pneumococcal pneumonia. The ICT was always negative in patients with non-pneumococcal pneumonia, but was positive in three cases with a non-infectious aetiology. In patients with pneumonia for which no pathogen was identified, antigen was detected in one of 24 pleural fluids tested. The ICT can be a valuable tool for the management of pneumonia because it can detect pneumococcal antigen in pleural effusion samples.
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