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  • Title: Development of leprosy and type 1 leprosy reactions after treatment with infliximab: a report of 2 cases.
    Author: Scollard DM, Joyce MP, Gillis TP.
    Journal: Clin Infect Dis; 2006 Jul 15; 43(2):e19-22. PubMed ID: 16779736.
    Abstract:
    Humanized monoclonal antibodies to tumor necrosis factor- alpha are valuable for the treatment of rheumatologic conditions, but they have been associated with the development of serious infections. We report the first 2 cases of leprosy developing after treatment with infliximab. After discontinuation of infliximab, both patients developed type 1 ("reversal") leprosy reactions.
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