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  • Title: Glomeruloid hemangioma leading to a diagnosis of POEMS syndrome.
    Author: Phillips JA, Dixon JE, Richardson JB, Fabre VC, Callen JP.
    Journal: J Am Acad Dermatol; 2006 Jul; 55(1):149-52. PubMed ID: 16781311.
    Abstract:
    POEMS is an acronym for polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes. It is a poorly understood paraneoplastic syndrome that stems from an underlying plasma cell dyscrasia. Of the skin changes, the glomeruloid hemangioma is considered to be a specific marker of POEMS syndrome. We describe a 68-year-old man who presented to his dermatologist with multiple hemangiomas, whose biopsy diagnosis of glomeruloid hemangioma resulted in further evaluation and an eventual diagnosis of POEMS.
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