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  • Title: L-nucleoside enantiomers as antivirals drugs: a mini-review.
    Author: Mathé C, Gosselin G.
    Journal: Antiviral Res; 2006 Sep; 71(2-3):276-81. PubMed ID: 16797735.
    Abstract:
    The discovery that some nucleoside analogues endowed with the unnatural L-configuration can possess biological activities has been a significant breakthrough in antiviral chemotherapy. In this regard, lamivudine (3TC) was the first L-nucleoside enantiomer approved against HIV and HBV, and several other L-nucleosides are currently under clinical development as antiviral agents.
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