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  • Title: Twenty years of paediatric cardiac pacing: 515 pacemakers and 480 leads implanted in 292 patients.
    Author: Silvetti MS, Drago F, Grutter G, De Santis A, Di Ciommo V, Ravà L.
    Journal: Europace; 2006 Jul; 8(7):530-6. PubMed ID: 16798767.
    Abstract:
    AIMS: The aim of this study was to evaluate long-term outcome of pacemakers (PMs) in paediatric patients. METHODS AND RESULTS: Patients' data were retrospectively reviewed. We recorded the techniques and systems used, any complication, and outcome. Endocardial leads were inserted by transcutaneous puncture of subclavian vein and fixed with a non-absorbable ligature, and epicardial leads by standard surgical technique. Lead survival was calculated and plotted with the product limit method of Kaplan-Meier. Between 1982 and 2002, 292 patients, aged 8+/-7 years (range 1 day-18 years), underwent PM implantation: the first PM had endocardial leads in 165 patients and epicardial in 127 patients. Structural heart disease (HD) was present in 239 patients. Follow-up was 5+/-4 (range 0.1-18) years. There were no pacing-related deaths. In total, 211 endocardial implantation procedures with 90 atrial and 165 ventricular leads and 145 epicardial procedures with 103 atrial and 123 ventricular leads were performed. Early (<3 months) complications: haemothorax occurred in 3.5% of endocardial leads and dislodgement was not significantly different for atrial and ventricular endocardial leads. Late complications: 63 leads failed (48 epicardial), with the worst outcome for conventional epicardial leads (31 vs. 9% endocardial, P<0.05; steroid eluting 8% epicardial vs. 5% endocardial, P=NS). Endocardial atrial leads failed (7%) in operated HD and ventricular leads failed (6%) after body growth, without difference in estimated mean survival time (11 years). Early and late PM infection/erosion was approximately 2% in all patients. CONCLUSION: Pacing in children shows good results, but complications are frequent and related to leads. Endocardial pacing showed better long-term outcome.
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