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  • Title: [The effect of gonadotropic hormones and the fetal hypophysis on testosterone production by the testis of 18 day mouse fetuses in organ culture].
    Author: Pointis G, Mahoudeau JA, Courrier R.
    Journal: C R Acad Hebd Seances Acad Sci D; 1975 May 26; 280(20):2361-4. PubMed ID: 167996.
    Abstract:
    The production of testosterone (measured by radioimmuno-assay) by the 18-day-old mouse fetal testis may be stimulated specifically by ovine LH (1 ng, p less than 0.005) and HCG in organ culture. A stimulation by FSH is observed only with high doses (10 mug, p less than 0.0005). Prolactin and ACTH have no effect. Age-matched fetal pituitaries increase significantly the testosterone production in the culture medium (p less than 0.0005).
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