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  • Title: Acute hemolysis with acute renal failure in a patient with valproic acid poisoning treated with charcoal hemoperfusion.
    Author: Rahman MH, Haqqie SS, McGoldrick MD.
    Journal: Hemodial Int; 2006 Jul; 10(3):256-9. PubMed ID: 16805886.
    Abstract:
    Hemoperfusion consists of the passage of anticoagulated blood through a column containing adsorbent particles. It was introduced in 1940 and refined from 1950 to 1970, and then introduced clinically for the treatment of acute intoxications between 1970 and 1980. Life-threatening valproic acid toxicity is an indication for coated charcoal hemoperfusion usually accomplished without complications, but we report a case of acute severe intravascular hemolysis during the time of hemoperfusion with coated charcoal column.
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