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  • Title: Traumatic dissociation, epileptic-like phenomena, and schizophrenia.
    Author: Bob P, Glaslova K, Susta M, Jasova D, Raboch J.
    Journal: Neuro Endocrinol Lett; 2006 Jun; 27(3):321-6. PubMed ID: 16807521.
    Abstract:
    OBJECTIVES: According to recent evidence, trauma and stress are important etiological factors in pathogenesis of schizophrenia. However, the hypothetical influence of traumatic stress on epileptic-like (or kindling) phenomena in schizophrenia is at this time unclear. METHODS: In order to discover the influence of trauma, 82 patients with a diagnosis of paranoid schizophrenia and 50 healthy controls were assessed for symptoms of dissociation, traumatic stress and psycho-sensory symptoms of epileptic origin. RESULTS: We have found significant traumatization and dissociation in patients who met the cut-off score for psychosensory epileptic-like symptoms and also significant correlations among these measures have been found. CONCLUSIONS: These data suggest a certain role of epileptic-like phenomena in dissociative states in schizophrenia and are in accordance with rare intracranial EEG findings which suggest a certain role of epileptiform events in schizophrenia.
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