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  • Title: [Selective apheresis of low-density lipoproteins].
    Author: Griskevicius A, Audzijoniene J.
    Journal: Medicina (Kaunas); 2006; 42(6):499-503. PubMed ID: 16816545.
    Abstract:
    The case of rare complicated homozygous hypercholesterolemia treated by a direct adsorption of lipoprotein apheresis procedure is presented in this article. In total eight sessions of direct adsorption of lipoprotein apheresis were performed on 14-year-old patient from June 2004 to January 2005. Blood flow rate was 30-50 ml/min. Central or ulnar veins were punctured. Lipids levels before and after lipid apheresis were measured during each session throughout the study period. The mean decrease in low-density lipoprotein cholesterol levels was 34.3-52.6% compared to baseline, total cholesterol--26.4-49.1%, lipoprotein (a)--67.4 and 90.9%, apolipoprotein B--26.4 and 48.4%. No side effects and complications were observed. The last four sessions were performed in a day unit.
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