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  • Title: Familial hypotrichosis of the scalp. Autosomal dominant inheritance in four generations.
    Author: Ibsen HH, Clemmensen OJ, Brandrup F.
    Journal: Acta Derm Venereol; 1991; 71(4):349-51. PubMed ID: 1681656.
    Abstract:
    We describe a Danish family of four generations suffering from hypotrichosis of the scalp. Age at onset was 6-17 years and almost total scalp alopecia was reached by the age of 14-21 years. No associated ectodermal defects were present. Nine of 22 persons covering four generations were affected. Growth of the scalp hair slowly decreased and was accompanied by a gradual, diffuse hair loss without regional variation. A scalp biopsy was performed, revealing a non-scarring alopecia with features of androgenetic alopecia. The pedigree was compatible with autosomal dominant inheritance.
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