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Title: Receptors as microprocessors: pharmacological nuance on metabotropic glutamate receptors 1alpha. Author: Kenakin T. Journal: Sci STKE; 2006 Jul 03; 2006(342):pe29. PubMed ID: 16818798. Abstract: G protein-coupled receptors have revealed themselves to be complex information-processing units that may be exploited for subtle therapeutic signaling effects. Thus, ligands may not only turn receptors on and off, but may also select from their repertoire of signaling effects to further refine drug response.[Abstract] [Full Text] [Related] [New Search]