These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Arterial hypertension: problems of maintenance therapy].
    Author: Kozlovskiĭ IV.
    Journal: Ter Arkh; 2006; 78(4):50-3. PubMed ID: 16821422.
    Abstract:
    AIM: To study hypotensive reactions in patients taking hypotensive drugs and to specify peculiarities of blood pressure elevation in patients with a long history of taking hypotensive drugs, especially atenolol. MATERIAL AND METHODS: ECG, ultrasound investigation, chest x-ray, cholesterol, lipoprotein, urea, creatinine assays, tests for serum transaminase and transpeptidase activity were made in 200 patients with essential hypertension of the 1-3 degree (110 males, 90 females, age 30-80 years) to elucidate effects of 24-h and prolonged administration of peripheral vasodilators, diuretics, beta-adrenoblockers. The following drugs were given: nitroglycerin (sublingually, 0.0005 g--3 tablets or intraveous drops), lasix (40 mg), anaprilin (0.04-0.12 g per os), verapamil (0.04 g) or nifedipine (0.01 g 3 times a day), enap or diroton (per os, once a day). Blood pressure was measured each 3-4 hours in the first 24 hours. CONCLUSIONS: Hypotensive drugs can normalize blood pressure and control it for a long time but their effect has some specific features. In hypertension of the 2-3 degree, beta-blockers are more effective than blockers of Ca channels, ACE, diuretics and nitroglycerin. Hypertensive patients on beta-adrenergic drugs maintenance have sometimes hypertensive crises which should be managed with nitroglycerin, ACE drugs (enap, as a rule) and diuretics (less frequently).
    [Abstract] [Full Text] [Related] [New Search]