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  • Title: Efficient high-throughput discovery of large peptidic hormones and biomarkers.
    Author: Taylor SW, Andon NL, Bilakovics JM, Lowe C, Hanley MR, Pittner R, Ghosh SS.
    Journal: J Proteome Res; 2006 Jul; 5(7):1776-84. PubMed ID: 16823986.
    Abstract:
    A novel approach is presented for the simultaneous identification and relative quantification of secreted peptides, particularly those that have been historically difficult to analyze in a concerted manner. Peptides exceeding 60 residues with various degrees of post-translational modification were identified on a liquid chromatographic time scale. The approach demonstrates high efficiency pattern-based recognition analysis of complex neuroendocrine peptide sets and enables rapid identification of biomarkers from biological material.
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