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  • Title: Tako-Tsubo-like syndrome during anaphylactic reaction.
    Author: Vultaggio A, Matucci A, Del Pace S, Simonetti I, Parronchi P, Rossi O, Maggi E, Gensini G, Romagnani S.
    Journal: Eur J Heart Fail; 2007 Feb; 9(2):209-11. PubMed ID: 16829194.
    Abstract:
    Tako-Tsubo's syndrome (apical ballooning or broken heart syndrome) is a reversible left ventricular dysfunction due to apical asynergy that occurs typically after sudden emotional stress in a subject without coronary disease. It is characterized by acute onset of chest pain or dyspnoea or both and is associated with electrocardiographic changes such as ST segment elevation and/or T wave inversion. Myocardial biomarkers may be normal or slightly elevated. Anaphylaxis is a severe, life-threatening, generalized hypersensitivity reaction, most often starting with urticaria and/or angioedema, that may involve cardiovascular and respiratory systems. Cardiovascular symptoms, including hypotension, cardiac arrhythmia and chest pain, are presumably linked to cardiac mast cell mediator release. We describe the case of a young woman who experienced a profound reversible cardiomyopathy with typical features of Tako-Tsubo's syndrome during an anaphylactic reaction.
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