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  • Title: [Renal amyloidosis complicating Crohn's disease: report of two cases and review of literature].
    Author: Elloumi H, Ben Slama A, Arfaoui D, Ghouma M, Sfar S, Ajmi S.
    Journal: Tunis Med; 2006 Apr; 84(4):253-5. PubMed ID: 16832997.
    Abstract:
    Secondary amyloidosis is caused by the extracellular store of the fragment AA of the circulatory protein in serum amyloid-A. It can complicate diseases such as family mediterranean fever, rheumatoid arthritis or Crohn's disease. Renal amyloidosis is a rare but serious complication of Crohn's disease. We report two cases of Crohn's disease associated with a nephrotic syndrome due to renal amyloidosis. It is important to recognize this complication, especially since Colchicine has been proposed as a possible treatment. So, the search for proteinuria seems to be important for an early diagnosis of renal amyloidosis in Crohn's disease.
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