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  • Title: [A case of long-term survival of gastric cancer with peritoneal metastasis effectively treated by TS-1 and paclitaxel (PTX) combination therapy].
    Author: Tanaka K, Kanamaru T, Yamamoto M.
    Journal: Gan To Kagaku Ryoho; 2006 Jul; 33(7):993-6. PubMed ID: 16835495.
    Abstract:
    We experienced the case of a 62-year-old woman who obtained long-term survival of three years by TS-1+paclitaxel (PTX) administration for gastric cancer postoperative peritoneal metastases. We first performed total gastrectomy, and the diagnosis was T3N2M0, Stage IIIB. Next, we performed chemotherapy by postoperative 5-FU+cisplatin (CDDP) and met in ambulatory. A bowel movement aberration was found during the course at 3 years postoperatively, and close inspection revealed sigmoid colon stenosis by peritoneal metastases. After construction of an artificial anus, we started administration of TS-1+paclitaxel. Chemotherapy was continued on an outpatient basis, and at-home treatment was possible for about 26 months till symptoms aggravated. No grave adverse event occurred except for depilation of grade 1. It was thought that this long-term treatment on an outpatient basis contributed to survival.
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