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  • Title: Pharmacological modulation by cetirizine and ebastine of the cutaneous reactivity to histamine.
    Author: Rivest J, Despontin K, Ghys L, Rihoux JP, Lachapelle JM.
    Journal: Dermatologica; 1991; 183(3):208-11. PubMed ID: 1683840.
    Abstract:
    The peripheral H1-inhibiting effects of cetirizine 10 mg and ebastine 10 mg were compared at the skin level after single oral administration. The study was performed in 9 healthy subjects under double-blind randomized crossover conditions. Both drugs were significantly effective up to 24 h. The suppressive effect of cetirizine was significantly more rapid and more marked.
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