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  • Title: An expeditious enantioselective total synthesis of valilactone.
    Author: Wu Y, Sun YP.
    Journal: J Org Chem; 2006 Jul 21; 71(15):5748-51. PubMed ID: 16839158.
    Abstract:
    The title compound was synthesized through an expeditious route using Crimmins aldolization to establish the two key stereogenic centers and a hydroxyl group activation (HGA) protocol to construct the anti alpha,beta-disubstituted beta-lactone from the corresponding syn aldol.
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