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  • Title: Evaluation of post-mortem ethanol concentrations in pericardial fluid and bone marrow aspirate.
    Author: Maeda H, Zhu BL, Ishikawa T, Oritani S, Michiue T, Li DR, Zhao D, Ogawa M.
    Journal: Forensic Sci Int; 2006 Sep 12; 161(2-3):141-3. PubMed ID: 16842951.
    Abstract:
    This study confirmed post-mortem ethanol concentrations in pericardial fluid and bone marrow aspirate in comparison with those in the blood in medicolegal autopsy cases (n = 140, within 48 h post-mortem). The specimens were examined by head-space gas chromatography/mass spectrometry. Ethanol concentrations in the pericardial fluid (y) were approximately equivalent to those in peripheral blood (x): y = 0.99x + 0.02, n = 44, r = 0.972. A high stomach ethanol concentration (>10 mg/ml) appeared to mildly affect the pericardial levels. There was no significant interference in drowning cases. Ethanol concentrations in bone marrow aspirates (y) also showed a good correlation with those in the peripheral blood (x): y = 0.77 x + 0.02, n = 20, r = 0.981. A dissociation was observed in cases of delayed death from hemorrhagic/traumatic shock and elderly victims. These findings suggest that pericardial fluid and bone marrow aspirate can be used as an alternative material when adequate blood specimens are not available.
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