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  • Title: Contrast ultrasound imaging of the carotid artery vasa vasorum and atherosclerotic plaque neovascularization.
    Author: Feinstein SB.
    Journal: J Am Coll Cardiol; 2006 Jul 18; 48(2):236-43. PubMed ID: 16843169.
    Abstract:
    Cardiovascular disease is associated with the aging of the population, obesity, metabolic syndrome, and diabetes. Therefore, it is important to develop non-invasive imaging systems to detect "at-risk" populations. New data suggest that contrast-enhanced ultrasound (CU) imaging of the carotid arteries enhances luminal irregularities (i.e., ulcers and plaques), improves near-wall, carotid intima-media thickness, and uniquely permits direct, real-time visualization of neovasculature of the atherosclerotic plaque and associated adventitial vasa vasorum. With continued clinical investigation, CU imaging of the carotid artery may afford an effective means to non-invasively identify atherosclerosis in "at-risk" populations while providing new standard for therapeutic monitoring.
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