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Title: Islet cell tumor. Author: Fitzpatrick B, Ordoñez NG, Mackay B. Journal: Ultrastruct Pathol; 1991; 15(4-5):579-84. PubMed ID: 1684455. Abstract: A case of islet cell tumor occurring in a patient with the multiple endocrine neoplasia type I syndrome is reported. Immunostaining for insulin was strongly positive in the tumor cells. Numerous dense-core granules of endocrine caliber were identified ultrastructurally. Morphometric analysis of the secretory granules in 20 islet cell tumors gave a granule size of 182 +/- 52 nm (mean +/- standard deviation).[Abstract] [Full Text] [Related] [New Search]