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  • Title: [Effect of eosin Y on ATPase activity of actomyosine complex of the uterus smooth muscle].
    Author: Labyntseva RD, Kosterin SO.
    Journal: Ukr Biokhim Zh (1999); 2005; 77(5):57-61. PubMed ID: 16846071.
    Abstract:
    The effect of eosin Y (2,4,5,7 - tetrabromofluorescein; 0.1-100 microM) on ATPase activity smooth muscle actomyosine was studied. The inhibition coefficient i50 of ATPase activity with eosin Y was 0.74 +/- 0.07 microM. The inhibitor decreased V(max) of actomyosine ATPase for ATP, but no influence on affinity of actomyosine for ATP was observed. It is suggested that eosin Y inhibits actomyosine ATPase activity noncompetitively in respect of ATP.
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