These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Adult neural stem cells express glucose transporters GLUT1 and GLUT3 and regulate GLUT3 expression.
    Author: Maurer MH, Geomor HK, Bürgers HF, Schelshorn DW, Kuschinsky W.
    Journal: FEBS Lett; 2006 Aug 07; 580(18):4430-4. PubMed ID: 16854415.
    Abstract:
    In the brain, glucose is transported by GLUT1 across the blood-brain barrier and into astrocytes, and by GLUT3 into neurons. In the present study, the expression of GLUT1 and GLUT3 mRNA and protein was determined in adult neural stem cells cultured from the subventricular zone of rats. Both mRNAs and proteins were coexpressed, GLUT1 protein being 5-fold higher than GLUT3. Stress induced by hypoxia and/or hyperglycemia increased the expression of GLUT1 and GLUT3 mRNA and of GLUT3 protein. It is concluded that adult neural stem cells can transport glucose by GLUT1 and GLUT3 and can regulate their glucose transporter densities.
    [Abstract] [Full Text] [Related] [New Search]