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  • Title: [Saponins of polygalacic acid type from Platycodon grandiflorum].
    Author: Fu WW, Hou WB, Dou DQ, Hua HM, Gui MH, Fu R, Chen YJ, Pei YH.
    Journal: Yao Xue Xue Bao; 2006 Apr; 41(4):358-60. PubMed ID: 16856483.
    Abstract:
    AIM: To isolate triterpene saponins of polygalacic acid type from the roots of Platycodon grandiflorum (Jacq.) A. DC and to identify their structures. METHODS: The compounds were separated by means of extraction, chromatography on silica gel, MPLC and HPLC, and their structures were elucidated on the basis of spectral analyses (FAB-MS, IR, 1H NMR, 13C NMR etc.). RESULTS: Three triterpene saponins were isolated from the roots of Platycodon grandiflorum. They were identified as 3-O-beta-D-laminaribiosyl polygalacic acid (I), 3-O-beta-D-glucopyranosyl polygalacic acid (II), polygalacin D (III), separately. CONCLUSION: Compound I is a new compound, compounds II, III are known triterpene saponins. The compound I and II were isolated from the plant for the first time, which is also the monodesmoside from the plant for the first time.
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