These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Exercises at different intensities and sequential changes of rat skeletal muscle cell apoptosis].
    Author: Cai BT, Yu B, Zhao JP, Zhang X.
    Journal: Nan Fang Yi Ke Da Xue Xue Bao; 2006 Jul; 26(7):1017-9. PubMed ID: 16864102.
    Abstract:
    OBJECTIVE: To study the effect of exercises of different intensities on rat skeletal muscle cell apoptosis. METHODS: Rat models of exhaustive exercise-induced skeletal muscle injury was established using tread mill exercises at different speeds, and the skeletal muscle cell apoptosis was detected using propidium iodide (PI) staining and flow cytometry. RESULT: No obvious gastrocnemius cell apoptosis was observed in rats with normal exercise (P>0.05), but the cell apoptosis index was statistically significant in moderate and exhaustive exercise groups (P<0.05), reaching the highest level in exhaustive exercise group after exercising. The gastrocnemius cell apoptosis index increased obviously on days 1 and 3 of exercise, and stabilized in moderate and exhaustive exercise groups. CONCLUSION: Exercises can evoke cell apoptosis and accelerate apoptotic cell clearance, and the imbalance between the two events during exercises may contribute to skeletal muscle injury.
    [Abstract] [Full Text] [Related] [New Search]