These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Analysis of some dosage forms containing pyridine derivatives using a cyclodextrin bonded stationary phase in HPLC.
    Author: El Gezawi S, Omar N, El Rabbat N, Perrin JH.
    Journal: J Pharm Biomed Anal; 1988; 6(4):393-8. PubMed ID: 16867405.
    Abstract:
    The high performance liquid chromatography of some pyridine derivatives using a silica column to which beta-cyclodextrin has been bonded, has been investigated. In spite of the low affinity constants of the drugs for cyclodextrin (of the order of 10(2) M(-1)) good separations can be achieved using a mobile phase of methanol and pH 7.0 phosphate. Good analysis of some dosage forms are achieved, including one on a tablet containing pheniramine maleate, pyrilamine maleate and phenylpropanolamine hydrochloride. Extractions and chromatography are quick and simple.
    [Abstract] [Full Text] [Related] [New Search]