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  • Title: Efficacy of betaxolol in neuroleptic-induced akathisia.
    Author: Adler LA, Angrist B, Rotrosen J.
    Journal: Psychiatry Res; 1991 Nov; 39(2):193-8. PubMed ID: 1686812.
    Abstract:
    Betaxolol, a beta 1-selective antagonist, produced marked improvement in eight patients with neuroleptic-induced akathisia. No further improvement was seen with subsequent propranolol treatment. These findings, along with the results of prior studies of betaxolol and metoprolol, suggest that blockade of central beta 1-receptors may be sufficient for efficacy in akathisia.
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