These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Moxifloxacin lethality against Mycobacterium tuberculosis in the presence and absence of chloramphenicol.
    Author: Malik M, Drlica K.
    Journal: Antimicrob Agents Chemother; 2006 Aug; 50(8):2842-4. PubMed ID: 16870782.
    Abstract:
    The C-8-methoxy fluoroquinolone moxifloxacin was more lethal against chloramphenicol-treated Mycobacterium tuberculosis than Bay y3114, a C-8-H cognate of moxifloxacin, and two C-8-methoxy fluoroquinolones, gatifloxacin and BMS-433368, which have different C-7 substituents. Thus, an optimal combination of C-7 and C-8 substituents is likely to be important for killing nongrowing M. tuberculosis.
    [Abstract] [Full Text] [Related] [New Search]