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  • Title: Labdanes and withanolides from Physalis coztomatl.
    Author: Pérez-Castorena AL, Oropeza RF, Vazquez AR, Martínez M, Maldonado E.
    Journal: J Nat Prod; 2006 Jul; 69(7):1029-33. PubMed ID: 16872139.
    Abstract:
    Aerial parts of Physalis coztomatl afforded a new labdane diterpene, physacoztomatin (1), and five new withanolides, physacoztolides A-E (5-9). Six known compounds were also isolated. The structures of the new compounds were established after analyses of their spectroscopic data and by means of chemical transformations. X-ray diffraction analyses of 15-dehydrophysacoztomatin (2) and 5 confirmed the structures of 1 and 5. Labd-13(E)-ene-8alpha,15-diol (4) and physacoztomatin (1) represent the first labdane diterpenes isolated from the genus Physalis.
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