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  • Title: [Prevalence of atopy and atopic diseases in children living in an orphanage in Lodz area--pilot study].
    Author: Stelmach I, Smejda K, Kaczmarek J, Stelmach W, Kuna P.
    Journal: Pol Merkur Lekarski; 2006 May; 20(119):531-4. PubMed ID: 16875155.
    Abstract:
    UNLABELLED: Over the past three decades there has been an increase in the prevelance of allergic diseases, specially among children. THE AIM OF THE STUDY: was to estimate the prevalence of atopy and atopic diseases in children who are living in orphanages in Lodz. MATERIAL AND METHODS: 120 children 5-18 years old living in 2 orphanages were studied. Main outcome measures were history, physical examination, FEV1, skin prick-test results with 18 allergens; peripheral blood eosinophil count, level of total and specific IgE in children with positive skin-test results were secondary and point. RESULTS: Bronchial asthma was diagnosed in 5.83% (6 of 120) patients, seasonal allergic rhinitis was diagnosed in 2.5% (3 of 120) patients and atopic dermatitis was diagnosed in 1.67% (2 of 120) patients. The skin prick-tests were positive in 12.5% children. Mean number of respiratory tracts infection in early childhood was significantly lower in atopic children than in non-atopic children--3.3 +/- 2,3 vs 8.7 +/- 2.5 (p<0.001). Mean total serum IgE concentration value reached upper limit in 26.6% of non-atopic patients and in 32.4% non-atopic children peripheral blood eosinophil count was significantly increased suggesting possible presence of active helminth infection, what might protect against atopy. CONCLUSION: In children living in orphanages we observed the lower prevalence of atopy (12.5%) and atopic diseases than in general population (25.4-40.2%).
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