These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Efficacy of probenecid for a patient with juvenile dermatomyositis complicated with calcinosis.
    Author: Nakamura H, Kawakami A, Ida H, Ejima E, Origuchi T, Eguchi K.
    Journal: J Rheumatol; 2006 Aug; 33(8):1691-3. PubMed ID: 16881125.
    Abstract:
    Calcinosis of juvenile dermatomyositis (JDM) is a crucial problem because it is refractory to various therapies. An 11-year-old boy who had been treated for JDM with interstitial pneumonia developed calcinosis of both legs despite treatment with corticosteroid and cyclosporin A. Images of his knees showed massive calcinosis with restricted range of motion. Probenecid was used to reduce calcinosis, resulting in remarkable improvement of calcinosis accompanied by normalization of serum phosphorus level and disability after 17 months of administration. We suggest that probenecid is useful for the treatment of calcinosis of JDM.
    [Abstract] [Full Text] [Related] [New Search]