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  • Title: IgE-mediated hypersensitivity reaction to lignocaine - a case report.
    Author: Noormalin A, Shahnaz M, Rosmilah M, Mujahid SH, Gendeh BS.
    Journal: Trop Biomed; 2005 Dec; 22(2):179-83. PubMed ID: 16883285.
    Abstract:
    We report a 7 year old girl who developed ipsilateral left facial swelling immediately after lignocaine injection. Skin prick test showed positive reaction to pure 2% lignocaine hydrochloride and to lignocaine oral dental gel. Specific Immunoglobulin E (Ig E) to lignocaine was detected. Lignocaine is a commonly used anaesthetic agent mainly as local anaesthesia. However type I hypersensitivity to lignocaine is rare and there have been very few cases reported in the literature.
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