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  • Title: Fogacin, a novel cyclic octaketide produced by Streptomyces strain Tü 6319.
    Author: Radzom M, Zeeck A, Antal N, Fiedler HP.
    Journal: J Antibiot (Tokyo); 2006 May; 59(5):315-7. PubMed ID: 16883783.
    Abstract:
    A new octaketide named fogacin (1) was isolated from Streptomyces sp. (strain Tü 6319). Furthermore two shunt metabolites, SEK4b (2) and anhydroSEK4b (3), were detected and identified as non-enzymatically cyclized products of polyketide intermediates built during the biosynthesis of actinorhodin. SEK4b (2) as well as anhydroSEK4b (3) were previously described as metabolites of genetically engineered strains.
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