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  • Title: A Mutation in the luxS gene influences Listeria monocytogenes biofilm formation.
    Author: Sela S, Frank S, Belausov E, Pinto R.
    Journal: Appl Environ Microbiol; 2006 Aug; 72(8):5653-8. PubMed ID: 16885324.
    Abstract:
    Using a Vibrio harveyi reporter strain, we demonstrated that Listeria monocytogenes secretes a functional autoinducer 2 (AI-2)-like signal. A luxS-deficient mutant produced a denser biofilm and attached to a glass surface 19-fold better than the parent strain. Exogenous AI-2 failed to restore the wild-type phenotype to the mutant. It seems that an intact luxS gene is associated with repression of components required for attachment and biofilm formation.
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