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  • Title: Production of resveratrol in recombinant microorganisms.
    Author: Beekwilder J, Wolswinkel R, Jonker H, Hall R, de Vos CH, Bovy A.
    Journal: Appl Environ Microbiol; 2006 Aug; 72(8):5670-2. PubMed ID: 16885328.
    Abstract:
    Resveratrol production in Saccharomyces cerevisiae was compared to that in Escherichia coli. In both systems, 4-coumarate:coenzyme A ligase from tobacco and stilbene synthase from grapes were expressed. When p-coumaric acid was used as the precursor, resveratrol accumulations in the culture medium were observed to be comparable in E. coli (16 mg/liter) and yeast (6 mg/liter).
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