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  • Title: [The kidneys and their vascular system in deficient inflow of arterial blood (an experimental study)].
    Author: Novikov IuV, Shormanov SV, Shormanov IS.
    Journal: Urologiia; 2006; (3):44-7. PubMed ID: 16889090.
    Abstract:
    Structural alterations of the kidneys and their vascular system were studied in condition of arterial circulation deficiency induced by narrowing of the isthmus of the aorta in 30 pups. The animals were followed up from 6 to 24 months. The model of chronic renal ischemia was achieved in which there was a fall in blood flow in the descending aorta and in pressure of blood coming to the kidneys. The capacity of the arterial part of the renal circulation with reactive thinning of the walls of renal arteries of different caliber was diminished. Adaptation of a part of these vessels caused closure rearrangement and decreased blood filling of glomerular capillaries with collaboration of some of them. The capacity of renal venous collectors increased due to blood deposit. Sclerotic changes of renal arteries, veins and glomeruli, atrophy of renal parenchyma, stromal overgrowth developed with time.
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