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  • Title: Host defense mechanisms against pathogens.
    Author: Accolla RS.
    Journal: Surg Infect (Larchmt); 2006; 7 Suppl 2():S5-7. PubMed ID: 16895506.
    Abstract:
    BACKGROUND AND PURPOSE: The body is under constant assault by potentially harmful microbes. Both innate and adaptive immune responses counteract the action of pathogens. METHOD: Review of the pertinent literature. RESULTS: The innate response is focused mainly on physically eliminating the pathogens, mostly by phagocytosis, while the adaptive response reacts specifically to, and neutralizes, a given pathogen and maintains a memory of it for safer and faster elimination on subsequent encounters. CONCLUSION: The basic mechanisms of pathogen elimination by the immune system and some mechanisms of evasion of the immune response by pathogens are discussed.
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