These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Phosphate group effects upon the equilibrium of iron(III) meso-tetrakis (4-N-methylpyridiniumyl) porphyrin in aqueous solution.
    Author: Santiago PS, Moreira LM, Tabak M.
    Journal: J Inorg Biochem; 2006 Nov; 100(11):1715-21. PubMed ID: 16899297.
    Abstract:
    Iron(III) meso-tetrakis (4-N-methylpyridiniumyl) porphyrin (FeTMPyP) undergoes a complex equilibrium in aqueous solution as a function of pH. Use of phosphate buffers, a common practice in biomedical applications of porphyrins, suggests the complexation of phosphate anion at the sixth coordination position to the iron, which contributes to the complexity of the equilibrium in the pH range from 1 to 4. In the absence of phosphate the equilibrium is simplified in a similar way as in the presence of high salt concentrations. Combined use of optical absorption, (1)H NMR and infrared spectroscopies, together with the literature data, suggest the formation of hexacoordinated monoaqueous-phosphate FeTMPyP complex in a limited acidic pH range. Discussion of the behavior of cationic FeTMPyP as compared to anionic iron(III) meso-tetrakis (4-sulfonatophenyl) porphyrin (FeTPPS(4)) is presented in regard to equilibrium of different species to explain the observed complex equilibrium.
    [Abstract] [Full Text] [Related] [New Search]