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  • Title: Biological effects of staphylococcal protein A immunotherapy in cats with induced feline leukemia virus infection.
    Author: Lafrado LJ, Mathes LE, Zack PM, Olsen RG.
    Journal: Am J Vet Res; 1990 Mar; 51(3):482-6. PubMed ID: 1690524.
    Abstract:
    Biological effects of staphylococcal protein A (SPA) immunotherapy were studied in 5 viremic and 6 nonviremic cats with induced FeLV infection and in 6 control cats. The SPA therapy neither reversed FeLV viremia nor resulted in consistent improvement in humoral immune responses to FeLV antigens. However, SPA immunotherapy induced a proliferative response in bone marrow granulocytic lineage, possibly resulting in expression of FeLV-free mature neutrophils in the blood. Seemingly, viral burden and chemiluminescent responses were reversed in viremic cats during SPA immunotherapy.
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