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  • Title: Huge intra- and extrathoracic lymphangioma in a baby successfully treated by sclerotherapy with OK-432.
    Author: Degenhardt P, Dieckow B, Mau H.
    Journal: Eur J Pediatr Surg; 2006 Jun; 16(3):197-200. PubMed ID: 16909360.
    Abstract:
    Lymphangiomas are rare congenital malformations of the lymphatic system. They typically appear within the first two years of life. They present as soft, indolent and benign tumors. As they have a tendency to grow in an infiltrating manner and rarely regress spontaneously, treatment may be necessary if the lymphangioma's location is functionally and cosmetically disturbing. Surgical therapy, which has been the treatment of choice so far, includes a risk of complications, depending on the location and extent of the tumor. Therefore alternative treatments such as sclerotherapy, especially with OK-432, have been developed. We present the case of a female baby with a huge macrocystic lymphangioma, extending over one half of the trunk, located intra- and extrathoracically, which was treated successfully by surgical resection and several intralesional injections of OK-432.
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