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  • Title: Tetraethylammonium stimulates adrenomedullary secretion by causing fluctuations in a cytosolic free Ca concentration.
    Author: Sorimachi M, Yamagami K, Nishimura S.
    Journal: Brain Res; 1990 Jan 22; 507(2):347-50. PubMed ID: 1692502.
    Abstract:
    Tetraethylammonium (TEA) caused marked fluctuations in a cytosolic free Ca concentration, which was measured by fura-2 microfluorimetry in bovine adrenal chromaffin cells. At the same time. TEA stimulated catecholamine secretion from cat and bovine chromaffin cells. Present results suggest that TEA indirectly increases the Ca2+ influx by depolarizing the cell membrane and consequently stimulates catecholamine secretion.
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