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  • Title: Serum antibodies to pneumococcal neuraminidase NanA in relation to pneumococcal carriage and acute otitis media.
    Author: Simell B, Jaakkola T, Lahdenkari M, Briles D, Hollingshead S, Kilpi TM, Käyhty H.
    Journal: Clin Vaccine Immunol; 2006 Oct; 13(10):1177-9. PubMed ID: 16928889.
    Abstract:
    Pneumococcal neuraminidase, NanA, is a pneumococcal vaccine candidate. Prior culture-confirmed pneumococcal contacts were shown to induce serum anti-NanA antibodies during the first 2 years of life. The antibody concentrations at neither 12 nor 18 months were significantly associated with the risk of subsequent pneumococcal carriage or acute otitis media.
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