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  • Title: Disodium pamidronate for treating severe hypercalcemia in a hemodialysis patient.
    Author: Trimarchi H, Lombi F, Forrester M, Elizondo C, Sawinski D, Pereyra H, Freixas E.
    Journal: Nat Clin Pract Nephrol; 2006 Aug; 2(8):459-63; quiz 464. PubMed ID: 16932480.
    Abstract:
    BACKGROUND: A 48-year-old man with a recent diagnosis of multiple myeloma and rapidly progressive oliguric end-stage renal disease requiring hemodialysis, presented with a serum calcium concentration of 3.4 mmol/l (13.6 mg/dl). INVESTIGATIONS: Serum laboratory analysis, electroencephalogram, MRI of the brain and bone marrow, and kidney biopsies. DIAGNOSIS: Hypercalcemia secondary to multiple myeloma. MANAGEMENT: Short-term intravenous disodium pamidronate therapy (30 mg daily) and daily monitoring of serum calcium concentration.
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