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  • Title: Demonstration of enzymes related to myelinogenesis in established human brain cell cultures.
    Author: Duch D, Mandel P, Koprowski H.
    Journal: J Neurol Sci; 1975 Sep; 26(1):99-105. PubMed ID: 169328.
    Abstract:
    CNP, CGalT and PAPS-CST, enzymes involved in myelinogenesis were demonstrated in cultures derived from human brain. Little or no CNP activity could be found in cultures derived from non-neurogenic tissue. Transformation of brain cultures by PML-SV40 virus resulted in a 3 to 10-fold increase in the specific activity of CNP.
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