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  • Title: Metabolic syndrome and the endocrine stress system.
    Author: Lamounier-Zepter V, Ehrhart-Bornstein M, Bornstein SR.
    Journal: Horm Metab Res; 2006 Jul; 38(7):437-41. PubMed ID: 16933178.
    Abstract:
    Obesity constitutes one of the most serious public health problems, with rapidly increasing prevalence in western societies. Consequently, metabolic syndrome, a condition strongly associated with obesity, has become an epidemic problem. Recent studies have implicated chronic alterations to the stress system as playing a major role in the metabolic syndrome's pathophysiology. This brief review discusses the role of stress and hypothalamic-pituitary-adrenal axis dysfunction in the development of metabolic syndrome as well as new insights into the crosstalk between adipose tissue and endocrine stress system.
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